drug metabolite — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
Fr13756	Isonicotinic acid		Endogenous Metabolite , Drug Metabolite
	Isonicotinic acid is a metabolite of Isoniazid.Isonicotinic acid is a useful isomer of nicotinic acid. Isoniazid is converted to Isonicotinic acid by hydrazinolysis, with the biotransformation also to be catalyzed by cyt...		Endogenous Metabolite , Drug Metabolite
T13539	Allopurinol riboside		Others , Endogenous Metabolite , Parasite , Drug Metabolite
	Allopurinol riboside is a metabolite of allopurinol with potency against parasites. Allopurinol riboside competitively inhibits the action of purine nucleoside phosphorylase on inosine with a Ki of 277 μM.		Others , Endogenous Metabolite , Parasite , Drug Metabolite
T16045	Methotrexate metabolite	DAMPA	Antifolate , Drug Metabolite
	Methotrexate metabolite (DAMPA) (DAMPA) is the active metabolite of Methotrexate. Methotrexate is a folic acid antagonist. Methotrexate is used as a chemotherapeutic agent and immunosuppressant.		Antifolate , Drug Metabolite
T12490	Pitavastatin lactone		Others
	Pitavastatin lactone is a major Pitavastatin metabolite in humans. Pitavastatin is a potent competitive inhibitor of HMG-CoA reductase little metabolized in hepatic microsomes.		Others
T8547	DCBA		Drug Metabolite
	DCBA, an endogenous metabolite of the insect repellent N-N-diethyl-meta-toluamide (DEET), is utilized to evaluate DEET exposure through its concentration levels in urine.		Drug Metabolite
T37514	Hydroxy Dimetridazole		Drug Metabolite
	Dimetridazole is a nitroimidazole-based compound with antibacterial and anticoccidial activity. It was once widely used in the treatment of parasitic infections in poultry, cattle, swine and farmed fish until suspected t...		Drug Metabolite
T13131	Tert-Buthyl Pitavastatin		HMG-CoA Reductase
	tert-Buthyl Pitavastatin is Pitavastatin metabolite. Pitavastatin is a potent inhibitor of HMG-CoA reductase.		HMG-CoA Reductase
T8115	Menthofuran		Others
	Menthofuran is a natural product.		Others
TN1740	Homoeriodictyol		5-HT Receptor , transporter , Sodium Channel , Drug Metabolite
	Homoeriodictyol, a naturally occurring, bitter-masking flavanone, as a promising agent to increase appetite and food intake. The flavanone homoeriodictyol can increase SGLT-1-mediated glucose uptake but decrease serotoni...
T3540	IMR-1A		Gamma-secretase , Drug Metabolite
	IMR-1A is the metabolite of IMR-1 which is a novel class of Notch inhibitors targeting the transcriptional activation with IC50 of 6 μMol/L.		Gamma-secretase , Drug Metabolite
T9344	3-Amino-2-oxazolidinone		Others , Endogenous Metabolite
	3-Amino-2-oxazolidinone (AOZ) is the metabolite of Furazolidone . It is always be detected as a indicator of furazolidone residues in vivo.		Others , Endogenous Metabolite
T13621	CNDAC hydrochloride		Nucleoside Antimetabolite/Analog , Others , Drug Metabolite
	CNDAC hydrochloride, a nucleoside analog, is a metabolite of the sapacitabine.		Nucleoside Antimetabolite/Analog , Others , Drug Metabolite
T12309	Omeprazole metabolite Omeprazole sulfone	Omeprazole sulphone,Omeprazole sulfone	Others
	Omeprazole metabolite Omeprazole sulfone can inhibit proton pump.		Others
T0668	1-Aminohydantoin hydrochloride		Others
	1-Aminohydantoin hydrochloride is a major metabolite of furantoin in animal tissues. It is covalently bound to tissue proteins, released from tissues under slightly acidic conditions, and can be detected by derivatizatio...		Others
T0150	Hydroxyhexamide	(±)-Hydroxyhexamid	Potassium Channel , Drug Metabolite
	Hydroxyhexamide ((±)-Hydroxyhexamid) is a pharmacologically active metabolite of Acetohexamide, used as a hypoglycemic agent.		Potassium Channel , Drug Metabolite
T38003	Levofloxacin N-oxide		Others
	Levofloxacin N-oxide is an inactive metabolite of the antibiotic levofloxacin . Levofloxacin N-oxide is also a degradation product of levofloxacin that is formed through exposure to daylight or hydrogen peroxide.		Others
T2687	Omeprazole sulfide	Omeprazole metabolite Omeprazole sulfide,Ufiprazole	Proton pump , Drug Metabolite
	Omeprazole sulfide (Ufiprazole), a metabolite of Omeprazole, functions as a proton pump inhibitor.		Proton pump , Drug Metabolite
T20723	LGE-899	Sonidegib metabolite M48,LGE 899	Drug Metabolite
	LGE-899 (Sonidegib metabolite M48) is a main metabolite of Sonidegib which is an inhibitor of the hedgehog pathway. The Tmax of LGE-899(60 h) is much longer than Sonidegib.		Drug Metabolite
T8217	Enzalutamide carboxylic acid		Androgen Receptor , Drug Metabolite
	Enzalutamide carboxylic acid is an antagonist of androgen receptor (AR) .		Androgen Receptor , Drug Metabolite
T10138	4-Desmethoxy Omeprazole		Drug Metabolite
	4-Desmethoxy Omeprazole is the active metabolite of Omeprazole. Omeprazole is a proton pump inhibitor (PPI). Omeprazole shows competitive inhibition of CYP2C19 activity (Ki: 2 to 6 μM).		Drug Metabolite